Eveniment

http://www.alertnet.org/thenews/newsdesk/L29222706.htm

AIDS expert reports progress towards HIV vaccine
30 Nov 2005 17:25:27 GMT
Source: Reuters
By Allyn Fisher-Ilan

JERUSALEM, Nov 30 (Reuters) - A scientist who helped to discover the HIV virus said he has made progress towards producing an AIDS vaccine and hopes to launch a clinical trial in about a year.

Dr. Robert Gallo, the director of the University of Maryland's Institute for Human Virology, said results from animal studies were encouraging.

"I think we've made some advances in making antibodies that will react with the variety of strains of HIV," he told Reuters, referring to the virus that causes AIDS.

Scientists believe a vaccine is the best hope for ending the global AIDS pandemic that has killed about 3.1 million people this year. But defeating the virus has proved more difficult than researchers had expected.

Gallo, in Israel to accept an award from Bar-Ilan University in advance of World AIDS day on Thursday, said it was still too early to say when a vaccine could be produced for humans.

Researchers believe an effective AIDS vaccine is still many years away.

"We have had some interesting results in the monkeys that show we can make an immune response,", Gallo said, noting potential progress on overcoming the problem of mutation of the virus.

But the antibodies produced in his experiments lasted only up to four months, which is far less than needed for an effective vaccine.

"We are making progress with a preventive vaccine, but we are not there yet," added Gallo, who discovered the AIDS virus with France's Luc Montagnier.

Earlier this week Europe's biggest drug maker GlaxoSmithKline Plc announced a plan to develop an experimental AIDS vaccine along with France's Institut Pasteur.

They intend to make the vaccine by fusing genes from HIV on to an existing vaccine for measles.

More than 30 AIDS vaccine trials in humans are ongoing but no one can predict if any will be effective against the virus that has infected nearly 5 million people in 2005.

Antiretroviral drugs have prolonged lives of people with HIV/AIDS but public health experts say preventing the spread of virus, by using condoms, abstinence and needle exchange programmes, is also essential for halting the epidemic.

The number of people living with HIV/AIDS hit a record high of 40.3 million this year, according to the latest figures from the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the World Health Organisation.

La 2005-12-01 12:40:42, RazvanM a scris:

> 
> http://www.alertnet.org/thenews/newsdesk/L29222706.htm
> 
> AIDS expert reports progress towards HIV vaccine
> 30 Nov 2005 17:25:27 GMT
> Source: Reuters
> By Allyn Fisher-Ilan
> 
> JERUSALEM, Nov 30 (Reuters) - A scientist who helped to discover the
> HIV virus said he has made progress towards producing an AIDS vaccine
> and hopes to launch a clinical trial in about a year.
> 
> Dr. Robert Gallo, the director of the University of Maryland's
> Institute for Human Virology, said results from animal studies were
> encouraging.
> 
> "I think we've made some advances in making antibodies that will
> react with the variety of strains of HIV," he told Reuters,
> referring to the virus that causes AIDS.
> 
> Scientists believe a vaccine is the best hope for ending the global
> AIDS pandemic that has killed about 3.1 million people this year. But
> defeating the virus has proved more difficult than researchers had
> expected.
> 
> Gallo, in Israel to accept an award from Bar-Ilan University in
> advance of World AIDS day on Thursday, said it was still too early to
> say when a vaccine could be produced for humans.
> 
> Researchers believe an effective AIDS vaccine is still many years
> away.
> 
> "We have had some interesting results in the monkeys that show we
> can make an immune response,", Gallo said, noting potential
> progress on overcoming the problem of mutation of the virus.
> 
> But the antibodies produced in his experiments lasted only up to four
> months, which is far less than needed for an effective vaccine.
> 
> "We are making progress with a preventive vaccine, but we are not
> there yet," added Gallo, who discovered the AIDS virus with
> France's Luc Montagnier.
> 
> Earlier this week Europe's biggest drug maker GlaxoSmithKline Plc
> announced a plan to develop an experimental AIDS vaccine along with
> France's Institut Pasteur.
> 
> They intend to make the vaccine by fusing genes from HIV on to an
> existing vaccine for measles.
> 
> More than 30 AIDS vaccine trials in humans are ongoing but no one can
> predict if any will be effective against the virus that has infected
> nearly 5 million people in 2005.
> 
> Antiretroviral drugs have prolonged lives of people with HIV/AIDS but
> public health experts say preventing the spread of virus, by using
> condoms, abstinence and needle exchange programmes, is also essential
> for halting the epidemic.
> 
> The number of people living with HIV/AIDS hit a record high of 40.3
> million this year, according to the latest figures from the Joint
> United Nations Programme on HIV/AIDS (UNAIDS) and the World Health
> Organisation.
> 


in mesaj se spune: "More than 30 AIDS vaccine trials in humans are ongoing but no one can predict if any will be effective against the virus that has infected nearly 5 million people in 2005".

va dau citeva informatii care pe unii ii vor shoca:
1. definitie: INFECTIE= capacitatea unui organism da a intra in organismul unui animal sau in organismul uman.
2. definitie: BOALA= capacitatea unui organism de a produce simtome, deci de a face pacientul sa simta ca ceva nu este in regula cu el.
Boala reprezinta : simtomele si schimbarile histopatogenice care se datoreaza infectiei initiale.
ex. foarte multi dintre pacientii care sint infectati cu microbul TUBERCULOZEI, INITIAL NU AU NICI-UN SIMTOM. nici macar nu stiu ca au fost infectati. dupa luni sau ani ei pot deveni bolnavi de tuberculoza.
BOLALA TB = febra, tuse, transpiratii nocturne, pierdere de greutate si RADIOGRAFII anormale.
INFECTIA TB= test positiv la tuberculina( testul cu roseata de pe mina care ni se facea la scoala), cu radiografie normala si pacientul simtindu-se"ca nou", deci fara simtome.

DECI INFECTIA NU ESTE EGALA CU BOALA..

VACCINELE NU PREVIN INFECTIILE, ele previn BOALA.
MOMENTUL ZERO=un vaccin produce anticorpi. in momentul in care microbul intra in organism ( momentul 1) sa ne atace celulele, acesti anticorpi ataca organismul respectiv ( sa zicem un virus HIV). multe virusuri mor , dar nu toate.
in acest moment ( momentul 1)sistemul imun incepe se se apere pe diverse cai aditional anticorpilor pe care ii avea deja, care de multe ori nu sint suficienti.
deci sint sintetizati anticorpi noi , se specializeaza si alte celule de lupta(imunitatea celulara), se elibereaza interferon si altele. impreuna aceasta armata distruge , in final, virusul.
LA MOMENTUL 1, cind virusul HIV a intrat deja in corpl nostru, primele celule pe care le infecteaza sint limfocitele CD4, fara de care sistemul imun uman nu poate functiona.
O SINGURA CELULA CD4 DACA ESTE INFECTATA, va fi extrem de dificil pentru corpul uman sa distruga toate virusurile HIV.
in acea celula infectata( CD4), virusul HIV este protejat de anticorpi.
el se poate CULCA SA FACA NANI, pentru ani de zile si nimeni nu-l va deranja.
peste citiva ani cind multi dintre anticorpii sintetzati de vaccin, sint mai putzini sau mai obositi, HOP-TZOP, virusul HIV incepe sa se inmulteasca, milioane de virusuri omoara in final celula CD4 si sint eliberati in singe.
anticorpii mai omoara din ei, dar citeva virusuri au timp sa mai infecteze alte celule CD4....si uite-asa pacientul ramine infectat cu HIV.

medicamentele distrug HIV numai daca acesta se afla in perioada de diviziune, deci virusurile care dorm nu sint afectate.

IN ISTORIA MEDICIENEI NU S-A INVENTAT UN VACCIN BUN IMPOTRIVA UNUI ORGANISM CARE DISTRUGE LIMFOCITELE CD4.

de aceea cu tehnologia de azi si cu modul in care specialistii gindesc vaccinele, NIMENI NU VA PUTEA FACE UN VACCIN IMPOTRIVA HIV.
respect!

pentru ca raspunsul imun de la momentul

... ca te-ai straduit sa ne explici lucrurile astea atit de complicate ... pe intelesul (atit cit se poate) nostru.
la fel si lui ... asclepios si lui ... cape3.

e o placere sa urmaresti oameni pasionali cu munca lor ...


La 2005-12-01 15:13:33, doctoru' a scris:

> in mesaj se spune: "More than 30 AIDS vaccine trials in humans
> are ongoing but no one can predict if any will be effective against
> the virus that has infected nearly 5 million people in 2005".
> 
> va dau citeva informatii care pe unii ii vor shoca:
> 1. definitie: INFECTIE= capacitatea unui organism da a intra in
> organismul unui animal sau in organismul uman.
> 2. definitie: BOALA= capacitatea unui organism de a produce simtome,
> deci de a face pacientul sa simta ca ceva nu este in regula cu el.
> Boala reprezinta : simtomele si schimbarile histopatogenice care se
> datoreaza infectiei initiale.
> ex. foarte multi dintre pacientii care sint infectati cu microbul
> TUBERCULOZEI, INITIAL NU AU NICI-UN SIMTOM. nici macar nu stiu ca au
> fost infectati. dupa luni sau ani ei pot deveni bolnavi de
> tuberculoza.
> BOLALA TB = febra, tuse, transpiratii nocturne, pierdere de greutate
> si RADIOGRAFII anormale.
> INFECTIA TB= test positiv la tuberculina( testul cu roseata de pe
> mina care ni se facea la scoala), cu radiografie normala si pacientul
> simtindu-se"ca nou", deci fara simtome.
> 
> DECI INFECTIA NU ESTE EGALA CU BOALA..
> 
> VACCINELE NU PREVIN INFECTIILE, ele previn BOALA.
>  MOMENTUL ZERO=un vaccin produce anticorpi. in momentul in care
> microbul intra in organism ( momentul 1) sa ne atace celulele, acesti
> anticorpi ataca organismul respectiv ( sa zicem un virus HIV). multe
> virusuri mor , dar nu toate.
> in acest moment ( momentul 1)sistemul imun incepe se se apere pe
> diverse cai aditional anticorpilor pe care ii avea deja, care de
> multe ori nu sint suficienti.
> deci sint sintetizati anticorpi noi , se specializeaza si alte celule
> de lupta(imunitatea celulara), se elibereaza interferon si altele.
> impreuna aceasta armata distruge , in final, virusul.
> LA MOMENTUL 1, cind virusul HIV a intrat deja in corpl nostru, primele
> celule pe care le infecteaza sint limfocitele CD4, fara de care
> sistemul imun uman nu poate functiona.
> O SINGURA CELULA CD4 DACA ESTE INFECTATA, va fi extrem de dificil
> pentru corpul uman sa distruga toate virusurile HIV.
> in acea celula infectata( CD4), virusul HIV este protejat de
> anticorpi.
> el se poate CULCA SA FACA NANI, pentru ani de zile si nimeni nu-l va
> deranja.
> peste citiva ani cind multi dintre anticorpii sintetzati de vaccin,
> sint mai putzini sau mai obositi, HOP-TZOP, virusul HIV incepe sa se
> inmulteasca, milioane de virusuri omoara in final celula CD4 si sint
> eliberati in singe.
> anticorpii mai omoara din ei, dar citeva virusuri au timp sa mai
> infecteze alte celule CD4....si uite-asa pacientul ramine infectat cu
> HIV.
> 
> medicamentele distrug HIV numai daca acesta se afla in perioada de
> diviziune, deci virusurile care dorm nu sint afectate.
> 
> IN ISTORIA MEDICIENEI NU S-A INVENTAT UN VACCIN BUN IMPOTRIVA UNUI
> ORGANISM CARE DISTRUGE LIMFOCITELE CD4.
> 
> de aceea cu tehnologia de azi si cu modul in care specialistii gindesc
> vaccinele, NIMENI NU VA PUTEA FACE UN VACCIN IMPOTRIVA HIV.
>  respect!
> 
> pentru ca raspunsul imun de la momentul
> 

La 2005-12-01 21:45:36, Seherezada a scris:

> 
> ... ca te-ai straduit sa ne explici lucrurile astea atit de complicate
> ... pe intelesul (atit cit se poate) nostru.
> la fel si lui ... asclepios si lui ... cape3.
> 
> e o placere sa urmaresti oameni pasionali cu munca lor ...
> 
> 
> La 2005-12-01 15:13:33, doctoru' a scris:
> 
> > in mesaj se spune: "More than 30 AIDS vaccine trials in humans
> > are ongoing but no one can predict if any will be effective against
> > the virus that has infected nearly 5 million people in 2005".
> > 
> > va dau citeva informatii care pe unii ii vor shoca:
> > 1. definitie: INFECTIE= capacitatea unui organism da a intra in
> > organismul unui animal sau in organismul uman.
> > 2. definitie: BOALA= capacitatea unui organism de a produce simtome,
> > deci de a face pacientul sa simta ca ceva nu este in regula cu el.
> > Boala reprezinta : simtomele si schimbarile histopatogenice care se
> > datoreaza infectiei initiale.
> > ex. foarte multi dintre pacientii care sint infectati cu microbul
> > TUBERCULOZEI, INITIAL NU AU NICI-UN SIMTOM. nici macar nu stiu ca au
> > fost infectati. dupa luni sau ani ei pot deveni bolnavi de
> > tuberculoza.
> > BOLALA TB = febra, tuse, transpiratii nocturne, pierdere de greutate
> > si RADIOGRAFII anormale.
> > INFECTIA TB= test positiv la tuberculina( testul cu roseata de pe
> > mina care ni se facea la scoala), cu radiografie normala si pacientul
> > simtindu-se"ca nou", deci fara simtome.
> > 
> > DECI INFECTIA NU ESTE EGALA CU BOALA..
> > 
> > VACCINELE NU PREVIN INFECTIILE, ele previn BOALA.
> >  MOMENTUL ZERO=un vaccin produce anticorpi. in momentul in care
> > microbul intra in organism ( momentul 1) sa ne atace celulele, acesti
> > anticorpi ataca organismul respectiv ( sa zicem un virus HIV). multe
> > virusuri mor , dar nu toate.
> > in acest moment ( momentul 1)sistemul imun incepe se se apere pe
> > diverse cai aditional anticorpilor pe care ii avea deja, care de
> > multe ori nu sint suficienti.
> > deci sint sintetizati anticorpi noi , se specializeaza si alte celule
> > de lupta(imunitatea celulara), se elibereaza interferon si altele.
> > impreuna aceasta armata distruge , in final, virusul.
> > LA MOMENTUL 1, cind virusul HIV a intrat deja in corpl nostru, primele
> > celule pe care le infecteaza sint limfocitele CD4, fara de care
> > sistemul imun uman nu poate functiona.
> > O SINGURA CELULA CD4 DACA ESTE INFECTATA, va fi extrem de dificil
> > pentru corpul uman sa distruga toate virusurile HIV.
> > in acea celula infectata( CD4), virusul HIV este protejat de
> > anticorpi.
> > el se poate CULCA SA FACA NANI, pentru ani de zile si nimeni nu-l va
> > deranja.
> > peste citiva ani cind multi dintre anticorpii sintetzati de vaccin,
> > sint mai putzini sau mai obositi, HOP-TZOP, virusul HIV incepe sa se
> > inmulteasca, milioane de virusuri omoara in final celula CD4 si sint
> > eliberati in singe.
> > anticorpii mai omoara din ei, dar citeva virusuri au timp sa mai
> > infecteze alte celule CD4....si uite-asa pacientul ramine infectat cu
> > HIV.
> > 
> > medicamentele distrug HIV numai daca acesta se afla in perioada de
> > diviziune, deci virusurile care dorm nu sint afectate.
> > 
> > IN ISTORIA MEDICIENEI NU S-A INVENTAT UN VACCIN BUN IMPOTRIVA UNUI
> > ORGANISM CARE DISTRUGE LIMFOCITELE CD4.
> > 
> > de aceea cu tehnologia de azi si cu modul in care specialistii gindesc
> > vaccinele, NIMENI NU VA PUTEA FACE UN VACCIN IMPOTRIVA HIV.
> >  respect!
> > 
> > pentru ca raspunsul imun de la momentul
> > 
> 
>-cu multa placere!
sper sa fi explicat bine si informatia sa fie folositoare.
sarbatori fericite!